Solutions for Genomic
and Epigenomic Research

Human Line 1 Assay
Analysis Results
Human Line 1, long interspersed elements, makes up about 15% of human genome and contain much of the CpG methylation
found in normal postnatal somatic tissues. Pyrosequencing methylation analysis of Line1 element can be used as a routine
method to measure global DNA methylation level in different human DNA samples.
Example of Control DNA:
Example of Treated DNA

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Global Methylation Analysis Services:
  •        We accept human genomic DNA for methylation analysis

  •        We offer a reliable analytical service in timely manner.

  •        We deliver quantitative results in percentage of methylation..
  •        We use Biotage's PyroMark Line 1 RUO for global methylation analysis.

  •        Four CpG dinucleotides are analyzed in each Line 1 element.

  •        Each of the four CpG sites can be partially methylated.